Novel synthesis, characterization and antimicrobial activity of some new 3,5-diarylpyrazolines

3-Aroyl flavanones were allowed to react with hydrazine hydrate in dioxane containing little piperidine to give corresponding 3-(2-hydroxyphenyl)-4-aroyl-5-aryipyrazolines. Their structural assignment are based on elemental analysis, spectral data (IR, UV & NMR) and chemical properties. All thes...

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Veröffentlicht in:Oriental journal of chemistry 2009-12, Vol.25 (4), p.1065-1069
Hauptverfasser: Bhise, M P, Raut, V M, Pawar, R P, Gulwade, G P, Junghare, NA, Murhekar, G H
Format: Artikel
Sprache:eng
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Zusammenfassung:3-Aroyl flavanones were allowed to react with hydrazine hydrate in dioxane containing little piperidine to give corresponding 3-(2-hydroxyphenyl)-4-aroyl-5-aryipyrazolines. Their structural assignment are based on elemental analysis, spectral data (IR, UV & NMR) and chemical properties. All these compounds were tested in vitro for their antibacterial activity by disk-diffusion method against gram positive and gram negative bacterias. In some of the compounds the results are found to be encouraging.
ISSN:0970-020X