Error-prone Gene mucAB Variants in Escherichia coli Plasmids from Japanese Donors

Variants of the error-prone gene, mucAB, were found in Escherichia coli plasmids from 3 out of 63 healthy Japanese donors. As compared with mucAB of pKM101, one contained unaltered mucA only, while two others contained full-sized, mutated mucAB with mutation-enhancing activity in E. coli. Possible i...

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Veröffentlicht in:Genes and Environment 2009, Vol.31(4), pp.119-122
Hauptverfasser: Tanooka, Hiroshi, Tatsumi, Kouichi, Tsuji, Hideo, Ochiya, Takahiro, Hirokawa, Hideo, Mitsuoka, Tomotari
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Sprache:eng
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Zusammenfassung:Variants of the error-prone gene, mucAB, were found in Escherichia coli plasmids from 3 out of 63 healthy Japanese donors. As compared with mucAB of pKM101, one contained unaltered mucA only, while two others contained full-sized, mutated mucAB with mutation-enhancing activity in E. coli. Possible interaction between bacterial plasmid genes and host humans was discussed.
ISSN:1880-7046
1880-7062
DOI:10.3123/jemsge.31.119