Synthesis and antimicrobial activity of 3H-1,2,4-thiadiazolo fused heterocycles

Various fused 3H‐1,2,4‐thiadiazoles were prepared. Significant in vitro Gram‐positive antibacterial and antifungal activities were observed for certain members of the series.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1979-02, Vol.68 (2), p.182-185
Hauptverfasser:	Gardner, John O., Beard, Colin C.
Format:	Artikel
Sprache:	eng
Schlagworte:	3H-1 3H‐1,2,4‐Thiadiazoles, various—synthesized, evaluated for antibacterial and antifungal activities in vitro 4-Thiadiazoles 4-thiadiazoles evaluated for antibacterial and antifungal activities in vitro 4-thiadiazoles evaluated in vitro Anti-Bacterial Agents Anti-Infective Agents - chemical synthesis Antibacterial activity-various 3H-1 Antibacterial activity—various 3H‐1,2,4‐thiadiazoles evaluated in vitro Antifungal activity-various 3H-1 Antifungal activity—various 3H‐1,2,4‐thiadiazoles evaluated in vitro Bacteria - drug effects evaluated for antibacterial and antifungal activities in vitro Fungi - drug effects Structure-Activity Relationship Structure-activity relationships-various 3H-1 Structure‐activity relationships—various 3H‐1,2,4‐thiadiazoles evaluated for antibacterial and antifungal activities in vitro Thiadiazoles - chemical synthesis Thiadiazoles - pharmacology various-synthesized
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Beschreibung
Zusammenfassung:	Various fused 3H‐1,2,4‐thiadiazoles were prepared. Significant in vitro Gram‐positive antibacterial and antifungal activities were observed for certain members of the series.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600680216