Human platelet monoamine oxidase activity in glaucoma

Monoamine oxidase (MAO, E.C. 1.4.3.4) activity was determined by spectrophotofluorimetric assay of the reaction product of the artificial substrate kynuramine in platelets from venous blood samples from 50 outpatients with glaucomas and 47 sex- and age-matched controls. No significant differences we...

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Veröffentlicht in:	Investigative ophthalmology & visual science 1979-03, Vol.18 (3), p.320-324
Hauptverfasser:	Aldinio, C, Cerletti, C, Manara, L, Recchia, M, Carlevaro, G, de Molfetta, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Blood Platelets - enzymology Eye Diseases - enzymology Female Glaucoma - diagnosis Glaucoma - enzymology Humans Male Middle Aged Monoamine Oxidase - analysis Sex Factors Spectrometry, Fluorescence
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Zusammenfassung:	Monoamine oxidase (MAO, E.C. 1.4.3.4) activity was determined by spectrophotofluorimetric assay of the reaction product of the artificial substrate kynuramine in platelets from venous blood samples from 50 outpatients with glaucomas and 47 sex- and age-matched controls. No significant differences were found between MAO activity in control subjects and that in subjects with glaucomas grouped according to diagnostic subcategories. Irrespective of ocular disease, women had significantly higher enzyme activity than men. Age-related changes in platelet MAO were inconsistent.
ISSN:	0146-0404 1552-5783