Potent dipsogenic effect of physalaemin in the pigeon

Physalaemin, injected by intracerebroventricular route to pigeons, elicited a powerful dipsogenic effect, even at doses as low as 10 ng/pigeon. No other behavioural alterations were observed at doses which elicited drinking behaviour. The dipsogenic potency of physalaemin proved to be inferior to th...

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Veröffentlicht in:Pharmacological research communications 1978-11, Vol.10 (10), p.861-866
Hauptverfasser: de Caro, G., Massi, M., Micossi, L.G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Physalaemin, injected by intracerebroventricular route to pigeons, elicited a powerful dipsogenic effect, even at doses as low as 10 ng/pigeon. No other behavioural alterations were observed at doses which elicited drinking behaviour. The dipsogenic potency of physalaemin proved to be inferior to that of angiotensin II, similar to that of eledoisin and far superior to that of substance P.
ISSN:0031-6989
1879-2936
DOI:10.1016/S0031-6989(78)80078-2