Hypermutation under stress

It is unclear whether the hypermutation observed in a recent study of the FC40 strain of the bacterium Escherichia coli has evolved as a means of overcoming nutritional stress (and thus whether it might have some evolutionary or ecological significance) or whether it is essentially a pathological re...

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Veröffentlicht in:Nature (London) 1997-06, Vol.387 (6633), p.557-558
1. Verfasser: Bridges, Bryn A
Format: Artikel
Sprache:eng
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Zusammenfassung:It is unclear whether the hypermutation observed in a recent study of the FC40 strain of the bacterium Escherichia coli has evolved as a means of overcoming nutritional stress (and thus whether it might have some evolutionary or ecological significance) or whether it is essentially a pathological response to damage accruing during the stress.
ISSN:0028-0836
1476-4687
DOI:10.1038/42370