The rules of attraction

The puzzle of how a drug that binds to a protein found in normal cells as well as cancer cells preferentially kills tumours is now solved. Apparently, the target protein exists in a drug-binding complex in tumor cells.

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Veröffentlicht in:Nature (London) 2003-09, Vol.425 (6956), p.357-359
Hauptverfasser: Neckers, Len, Lee, Yong-Sok
Format: Artikel
Sprache:eng
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Zusammenfassung:The puzzle of how a drug that binds to a protein found in normal cells as well as cancer cells preferentially kills tumours is now solved. Apparently, the target protein exists in a drug-binding complex in tumor cells.
ISSN:0028-0836
1476-4687
DOI:10.1038/425357a