C. elegans genome sequencing project: a beginning

The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisi...

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Veröffentlicht in:	Nature (London) 1992-03, Vol.356 (6364), p.37-41
Hauptverfasser:	Sulston, J, Du, Z, Thomas, K, Wilson, R, Hillier, L, Staden, R, Halloran, N, Green, P, Thierry-Mieg, J, Qiu, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Caenorhabditis - genetics Caenorhabditis elegans Chromosome Mapping Classical genetics, quantitative genetics, hybrids clones Cosmids - genetics Deoxyribonucleic acid DNA Fundamental and applied biological sciences. Psychology Gene Library genes Genetics Genetics of eukaryotes. Biological and molecular evolution Genome genomics Humanities and Social Sciences Invertebrata Mammals molecular sequence data multidisciplinary nucleotide sequences Science Science (multidisciplinary)
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Beschreibung
Zusammenfassung:	The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/356037a0