Healthy Animals with Extreme Longevity

In the nematode Caenorhabditis elegans, mutations that inhibit insulin/IGF-1 (insulin-like growth factor 1) signaling, such as daf-2 insulin/IGF-1 receptor mutations, can double their life-span of the animal. Removing the germ-line precursor cells also extends lifespan by approximately 60 percent. R...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2003-10, Vol.302 (5645), p.611-611
Hauptverfasser:	Arantes-Oliveira, Nuno, Berman, Jennifer R., Kenyon, Cynthia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Biophysics Brevia Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - physiology Fundamental and applied biological sciences. Psychology Genes, Helminth Genetic aspects Genetic mutation Genetics Germ cells Gonads Gonads - physiology Insulin Invertebrates Longevity Movement Mutation Nemathelminthia. Plathelmintha Physiological aspects Physiology. Development Receptor, Insulin - genetics Receptor, Insulin - physiology RNA Interference
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