Glia-synapse interaction through Ca(2+)-permeable AMPA receptors in Bergmann Glia

Glia-synapse interaction through Ca(2+)-permeable AMPA receptors in Bergmann Glia

Glial cells express a variety of neurotransmitter receptors. To elucidate the role of Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type glutamate receptors (AMPARs), Iino et al converted them into CA2+-impermeable receptors by adenoviral-mediated delivery of the GluR...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2001-05, Vol.292 (5518), p.926-929
Hauptverfasser: Iino, Masae, Goto, Kaori, Kakegawa, Wataru, Okado, Haruo
Format: Artikel
Sprache:eng
Schlagworte:
Cells
Cellular biology
Neurology
Neurons
Neurotransmitters
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Zusammenfassung:Glial cells express a variety of neurotransmitter receptors. To elucidate the role of Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type glutamate receptors (AMPARs), Iino et al converted them into CA2+-impermeable receptors by adenoviral-mediated delivery of the GluR2 gene.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1058827