A glimmer of light for neuropsychiatric disorders

Understanding the pathogenesis of neuropsychiatric disorders is a substantial challenge for neurobiologists. It has long been hoped that identifying alleles that confer increased risk of such disorders would provide clues for neurobiological investigation. But this quest has been stymied by a lack o...

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Veröffentlicht in:	Nature (London) 2008-10, Vol.455 (7215), p.890-893
1. Verfasser:	Hyman, Steven E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Bipolar disorder Development and progression Drugs Genetic aspects Genetic linkage Human capital Humanities and Social Sciences Humans introduction Medical research Mental Disorders - diagnosis Mental Disorders - epidemiology Mental Disorders - genetics Mental Disorders - physiopathology Mental illness Mortality multidisciplinary Mutation Nervous System Diseases - diagnosis Nervous System Diseases - epidemiology Nervous System Diseases - genetics Nervous System Diseases - physiopathology Neurosciences Phenotype Reverse engineering Risk factors Schizophrenia Science Science (multidisciplinary) Studies
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Beschreibung
Zusammenfassung:	Understanding the pathogenesis of neuropsychiatric disorders is a substantial challenge for neurobiologists. It has long been hoped that identifying alleles that confer increased risk of such disorders would provide clues for neurobiological investigation. But this quest has been stymied by a lack of validated biological markers for characterizing and distinguishing the different disorders and by the genetic complexity underpinning these diseases. Now, modern genomic technologies have begun to facilitate the discovery of relevant genes.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/nature07454