GABA Becomes Exciting

GABA Becomes Exciting

Researchers have shed light on the underlying causes of epileptic seizures with their in vitro study of brain tissue from 21 patients with temporal lobe epilepsy. Their findings suggest that interneurons producing the inhibitory neurotransmitter GABA together with aberrantly behaving excitatory pyra...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2002-11, Vol.298 (5597), p.1350-1351
1. Verfasser: Kohling, Rudiger
Format: Artikel
Sprache:eng
Schlagworte:
Action potentials
Behavioral neuroscience
Brain
Epilepsy
GABA
GABA receptors
Interneurons
Medical research
Narcotics
Neurology
Neurons
Neurotransmitter receptors
Patients
Perspectives
Principals
Receptors
Seizures
Synapses
Synaptic transmission
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Zusammenfassung:Researchers have shed light on the underlying causes of epileptic seizures with their in vitro study of brain tissue from 21 patients with temporal lobe epilepsy. Their findings suggest that interneurons producing the inhibitory neurotransmitter GABA together with aberrantly behaving excitatory pyramidal neurons in the hippocampal region can precipitate epileptic seizures.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1079446