Adsorption of human IgG on to poly(N-isopropylacrylamide)-based polymer particles

Thermosensitive poly(N-isopropylacrylamide)-based polymer particles were synthesised, and screened for the adsorption of human immunoglobulin G (hIgG). At pH 9 the adsorption on microgel particles was strongly affected by temperature, approximately 40 mg hIgG/g support (90% of initial hIgG) being ad...

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Veröffentlicht in:	Biotechnology letters 2006-12, Vol.28 (24), p.2019-2025
Hauptverfasser:	Silva, Claudia S. O, Baptista, Ricardo P, Santos, Andrea M, Martinho, José M. G, Cabral, Joaquim M. S, Taipa, M. Ângela
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamides - pharmacokinetics Acrylic Resins Adsorption Biological and medical sciences Biotechnology Fundamental and applied biological sciences. Psychology Human immunoglobulin G Humans Hydrogen-Ion Concentration Immunoglobulin G - chemistry Immunoglobulin G - metabolism Nanoparticles - chemistry Poly(methyl methacrylate) Poly(N-isopropylacrylamide) Polymers Polymers - chemistry Polymers - pharmacokinetics Temperature Thermosensitive polymers Time Factors
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