Biomarkers of Caloric Restriction May Predict Longevity in Humans

The most robust intervention for slowing aging and maintaining health and function in animals is dietary caloric restriction (CR). Although most studies have been conducted in rodents and lower animals, data accumulating from rhesus monkeys suggest that CR may also be relevant for primates, includin...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2002-08, Vol.297 (5582), p.811-811
Hauptverfasser:	Roth, George S., Lane, Mark A., Ingram, Donald K., Mattison, Julie A., Elahi, Dariush, Tobin, Jordan D., Muller, Denis, Metter, E. Jeffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging - blood Analysis Animals Attrition (Research Studies) Biological and medical sciences Biological markers Biomarkers - blood Body Temperature Brevia Caloric content Calories Climate Dehydroepiandrosterone Sulfate - blood Development. Metamorphosis. Moult. Ageing Diet Energy Intake - physiology Food Fundamental and applied biological sciences. Psychology Health aspects Human aging Humans Insulin Insulin - blood Life Expectancy Longevity Longevity - physiology Longitudinal Studies Macaca mulatta - blood Macaca mulatta - physiology Male Male animals Males Medical research Middle Aged Monkeys & apes Mortality Primates Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Beschreibung
Zusammenfassung:	The most robust intervention for slowing aging and maintaining health and function in animals is dietary caloric restriction (CR). Although most studies have been conducted in rodents and lower animals, data accumulating from rhesus monkeys suggest that CR may also be relevant for primates, including humans.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.1071851