Breaching the Barrier

The identification of more than 360 families of transporters through biochemical and genomic analyses highlights the importance of transport processes to cells. Locher et al stress the need to breach the major barriers to the structural determination of membrane proteins. The functions of the bacter...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2003-08, Vol.301 (5633), p.603-604
Hauptverfasser:	Locher, Kaspar P., Bass, Randal B., Rees, Douglas C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Cellular biology Crystallography Cytoplasm Membrane proteins Membranes Perspectives Phosphates Photons Polarized light Porters Proteins String theory
Online-Zugang:	Volltext
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Zusammenfassung:	The identification of more than 360 families of transporters through biochemical and genomic analyses highlights the importance of transport processes to cells. Locher et al stress the need to breach the major barriers to the structural determination of membrane proteins. The functions of the bacterial transporters LacY and GlpT structures are examined.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.1088621