Hypothalamic hyperphagia prevented by prior subdiaphragmatic vagotomy: Insulin hyperphagia is unaffected

Hypothalamic hyperphagia prevented by prior subdiaphragmatic vagotomy: Insulin hyperphagia is unaffected

Male rats were given bilateral subdiaphragmatic vagotomy or a sham operation. Both groups of animals showed equivalent hyperphagia and weight gain during a ten day treatment with long-acting insulin. Despite this ability to increase feeding, the vagotomized rats did not overeat and become obese afte...

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Veröffentlicht in:Physiology & behavior 1978-11, Vol.21 (5), p.685-689
Hauptverfasser: Rowland, Neil, Engle, David J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Body Weight
Brain Mapping
Diet
Feeding Behavior - drug effects
Feeding Behavior - physiology
Gastrointestinal motility
Hyperphagia
Hypothalamus - physiology
Hypothalamus, Middle - physiology
Insulin
Insulin - pharmacology
Male
Rats
Vagotomy
Vagus Nerve - physiology
VMH lesion
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Beschreibung
Zusammenfassung:Male rats were given bilateral subdiaphragmatic vagotomy or a sham operation. Both groups of animals showed equivalent hyperphagia and weight gain during a ten day treatment with long-acting insulin. Despite this ability to increase feeding, the vagotomized rats did not overeat and become obese after VMH lesions.
ISSN:0031-9384
1873-507X
DOI:10.1016/0031-9384(78)90003-3