The potential role of In-111 white blood cell scans in patients with inflammatory bowel disease

In many institutions, the use of In-111 white blood cell (WBC) scans have become routine for abscess detection. Its use for the detection of bone and joint inflammation, renal disease, and myocardial infarction has also been reported. Two patients are presented whose In-111 studies were of major clinical value in the management of their inflammatory bowel disease. In one, the diagnosis was suggested, and in the second, the extent of disease was defined. The potential role of In-111 WBC imaging in inflammatory bowel disease--for diagnosis, staging, and monitoring response to therapy--are discussed. Possible pitfalls as well as a comprehensive prospective study are suggested.