BIOLOGICAL ACTIVITY OF (5R, 6S, 8R)-6-α-HYDROXYETHYL-2- ACETOXYMETHYL-2-PENEM-3-CARBOXYLATE

The authors describe the physicochemical properties and the biological activity of 6- alpha -hydroxyethyl penems which possess, at one and the same time the natural side chain of thienamycin and the cephalosporin functionality.

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Veröffentlicht in:Journal of antibiotics 1982, Vol.35(9), pp.1248-1251
Hauptverfasser: SANFILIPPO, AURORA, BRUNA, COSTANTINO DELLA, JABES, DANIELA, MORVILLO, ENZA, SCHIOPPACASSI, GIOVANNA, FRANCESCHI, GIOVANNI, ARCAMONE, FEDERICO, BATTISTINI, CARLO, FOGLIO, MAURIZIO, ZARINI, FRANCO
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container_end_page 1251
container_issue 9
container_start_page 1248
container_title Journal of antibiotics
container_volume 35
creator SANFILIPPO, AURORA
BRUNA, COSTANTINO DELLA
JABES, DANIELA
MORVILLO, ENZA
SCHIOPPACASSI, GIOVANNA
FRANCESCHI, GIOVANNI
ARCAMONE, FEDERICO
BATTISTINI, CARLO
FOGLIO, MAURIZIO
ZARINI, FRANCO
description The authors describe the physicochemical properties and the biological activity of 6- alpha -hydroxyethyl penems which possess, at one and the same time the natural side chain of thienamycin and the cephalosporin functionality.
doi_str_mv 10.7164/antibiotics.35.1248
format Article
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subjects Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Cefotaxime - pharmacology
Chemical Phenomena
Chemistry, Physical
Clostridium perfringens
Lactams
Listeria
staphylococcus
streptococcus
Time Factors
title BIOLOGICAL ACTIVITY OF (5R, 6S, 8R)-6-α-HYDROXYETHYL-2- ACETOXYMETHYL-2-PENEM-3-CARBOXYLATE
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