Induction of chicken interferon by avian infectious bronchitis virus

Induction of chicken interferon by avian infectious bronchitis virus

The ability of nine strains of avian infectious bronchitis virus (IBV) to induce chicken interferon has been investigated using Semliki Forest virus for the tests. The Beaudette, H120 and Connecticut 46 strains induced interferon in the allantoic fluids of embryonated hens’ eggs, the highest titre (...

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Veröffentlicht in:Research in veterinary science 1978-09, Vol.25 (2), p.178-181
Hauptverfasser: Holmes, H.C., Darbyshire, J.H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Avian infectious bronchitis
Bronchitis
Cells, Cultured
Chick Embryo
Chickens
Coronaviridae - drug effects
Coronaviridae - metabolism
Eggs
Embryos
Infectious bronchitis virus - drug effects
Infectious bronchitis virus - metabolism
Infectious diseases
Interferon
Interferons - biosynthesis
Interferons - pharmacology
Kidneys
Poultry
RNA, Viral - biosynthesis
Strains (organisms)
Trachea
Veterinary medicine
Viruses
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Zusammenfassung:The ability of nine strains of avian infectious bronchitis virus (IBV) to induce chicken interferon has been investigated using Semliki Forest virus for the tests. The Beaudette, H120 and Connecticut 46 strains induced interferon in the allantoic fluids of embryonated hens’ eggs, the highest titre (1:30) being associated with Beaudette; but these as well as the Massachusetts M-41 and H52 strains failed to yield interferon in primary monolayer cultures of chick kidney ceils as did all nine strains in organ cultures of chick embryo trachea. None of six strains of IBV investigated was susceptible to the inhibitory effects of chicken interferon.
ISSN:0034-5288
1532-2661
DOI:10.1016/S0034-5288(18)32975-8