Complexes of group IIA cations with adenosine 5′-triphosphate

The infrared and Raman spectra of the disodium salts of magnesium and calcium with adenosine 5′-triphosphate (ATP) along with the Be 2+, Mg 2+, Ca 2+, Sr 2+, and Ba 2+ salts with H 2ATP 2− and Ca 2+, Sr 2+ and Ba 2+ salts with ATP 4− in the solid state are reported and the structural implications of these data considered. The infrared and Raman findings for the disodium salts of ATP with calcium and magnesium are in disagreement with earlier conclusions that ATP −4 is acting as a tetradentate ligand. Similarities among the spectra of all substances suggest that the group IIA cations interact mainly with the β- and γ-phosphates of ATP, in accordance with studies in aqueous solutions.