Regulation of glucose metabolism in the lung: Hexokinase-catalyzed phosphorylation, a rate-limiting step

Regulation of glucose metabolism in the lung: Hexokinase-catalyzed phosphorylation, a rate-limiting step

A measurement of uptake and phosphorylation of 2-deoxyglucose in rat lung slices under appropriately designed conditions showed that glucose metabolism in lung at the physiological concentration of the sugar will be limited by the rate of its phosphorylation and not by its transport into the cells.

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Veröffentlicht in:Life sciences (1973) 1982-08, Vol.31 (8), p.791-794
Hauptverfasser: Salotra, Poona Talwar, Singh, Vishwa N.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological Transport
Glucose - metabolism
Hexokinase - metabolism
In Vitro Techniques
Lung - metabolism
Male
Phosphorylation
Rats
Rats, Inbred Strains
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Zusammenfassung:A measurement of uptake and phosphorylation of 2-deoxyglucose in rat lung slices under appropriately designed conditions showed that glucose metabolism in lung at the physiological concentration of the sugar will be limited by the rate of its phosphorylation and not by its transport into the cells.
ISSN:0024-3205
1879-0631
DOI:10.1016/0024-3205(82)90706-8