Annotation on Stem Cells and Differentiation Fields

Annotation on Stem Cells and Differentiation Fields

Gradient dynamics are elaborated in the context of a differentiation field to account for stem cells renewal and terminal differentiation. The rapidly emerging non-linearities are discussed in relationship to normal and malignant differentiation, and used to explain the progression to autonomous gro...

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Veröffentlicht in:Differentiation (London) 1982-05, Vol.21 (1), p.139-148
1. Verfasser: MATIOLI, GASTONE TERENZIO
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Count
Cell Differentiation
Cell Transformation, Neoplastic
Hematopoietic Stem Cells - cytology
Hematopoietic Stem Cells - pathology
Humans
Leukemia - pathology
Mathematics
Models, Biological
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Beschreibung
Zusammenfassung:Gradient dynamics are elaborated in the context of a differentiation field to account for stem cells renewal and terminal differentiation. The rapidly emerging non-linearities are discussed in relationship to normal and malignant differentiation, and used to explain the progression to autonomous growth.
ISSN:0301-4681
1432-0436
DOI:10.1111/j.1432-0436.1982.tb01207.x