Circulating Immune Complexes and the Prognosis of Acute Myeloid Leukemia

We studied the relation between the clinical course and the presence of circulating immune complexes at diagnosis and/or during complete remission in 186 patients with acute myeloid leukemia. Patients with immune complexes at diagnosis had significantly fewer complete remissions (32 vs. 94 per cent)...

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Veröffentlicht in:	The New England journal of medicine 1982-11, Vol.307 (19), p.1174-1180
Hauptverfasser:	Carpentier, Nicole A, Fiere, Denis M, Schuh, Daniel, Lange, Ghislaine T, Lambert, Paul-Henri
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Antibiotics Antigen-Antibody Complex - analysis Antigen-antibody complexes Blood & organ donations Cancer therapies Chemotherapy Diagnosis Disease Erythrocytes Failure Hematology Humans Leukemia Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - immunology Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Medical prognosis Middle Aged Myeloid leukemia Prognosis Remission Time Factors
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Zusammenfassung:	We studied the relation between the clinical course and the presence of circulating immune complexes at diagnosis and/or during complete remission in 186 patients with acute myeloid leukemia. Patients with immune complexes at diagnosis had significantly fewer complete remissions (32 vs. 94 per cent), remissions of shorter duration (median, 4.3 vs. 15.0 months), and shorter survival times (median, 1.8 vs. 22.3 months) than patients without such complexes (all comparisons, P
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJM198211043071903