Protective properties of the cavitary fluid antigens of Ascaris suum

Fractions of cavitary fluid of Ascaris (CFA) containing antigens were obtained on membranous filters. Being administered to mice they provide the development of protective immunity of animals to their subsequent infection with invasional eggs of A. suum. In mice immunized with fraction CFA XM-50 the number of A. suum larvae obtained from the lungs on the 7th day of invasion was confidentially lower than in control animals (15.277) +/- 1.825 on the 7th day of invasion was confidentially lower than in control animals (15.277 +/- 1.825 and 58.10 +/- 1.588, respectively, p less than 0.001). Immunisation of mice with fraction XM-300 caused less pronounced protective effect. Low-molecular antigens of the fraction UM-05 possess tolerant properties. In mice immunized with fraction UM-05 the number of A. suum larvae obtained from the lungs on the 7th day after invasion was greater than in control ones (68.22 +/- 6.24 and 49.39 +/- 4.13, respectively, p less than 0.001).