Mechanism of Phage Mu-1 Integration: Nalidixic Acid Treatment Causes Clustering of Mu-1-Induced Mutations near Replication Origin

Frequencies of Mu-1-induced mutants of Escherichia coli have been compared under two different experimental conditions: cells in exponential growth and the same cells treated with nalidixic acid. The average of values obtained from the nalidixic acid-treated culture is 3 times higher than that obtai...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1978-10, Vol.75 (10), p.4940-4943
Hauptverfasser:	Paolozzi, Luciano, Jucker, Richard, Calef, Enrico
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid treatment Bacteriophages Coliphages - genetics DNA DNA Replication DNA, Bacterial - metabolism Genetic mutation Infections Lysogeny Nalidixic Acid - pharmacology Parasite hosts Replication origin Sugars Virology
Online-Zugang:	Volltext
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