Immunologic Relationship Between Breast Carcinoma and Benign Breast Disease as Detected by the Leukocyte Migration Inhibition Assay

Immunologic Relationship Between Breast Carcinoma and Benign Breast Disease as Detected by the Leukocyte Migration Inhibition Assay

Peripheral blood and regional lymph node mononuclear cells from 43 untreated patients with breast cancer were analyzed for the proportions of total T-cells and T-cells with receptors for the Fc portion of IgM (Tμ), IgG (Tγ), or IgA (Tα). Proportions of total T-cells and Tμ cells both in peripheral b...

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Veröffentlicht in:JNCI : Journal of the National Cancer Institute 1978-11, Vol.61 (5), p.1181-1186
Hauptverfasser: Cannon, G. B., McCoy, J. L., Jerome, L. J., Reddick, R., Alford, C., Tinley, V., Herberman, R. B.
Format: Artikel
Sprache:eng
Schlagworte:
Adenofibroma - immunology
Antigens, Neoplasm
Breast Diseases - immunology
Breast Neoplasms - immunology
Cell Line
Cell Migration Inhibition
Female
Humans
Immunity, Cellular
In Vitro Techniques
Leukocytes - immunology
Male
Neoplasms, Experimental - immunology
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Zusammenfassung:Peripheral blood and regional lymph node mononuclear cells from 43 untreated patients with breast cancer were analyzed for the proportions of total T-cells and T-cells with receptors for the Fc portion of IgM (Tμ), IgG (Tγ), or IgA (Tα). Proportions of total T-cells and Tμ cells both in peripheral blood and lymph nodes from breast cancer patients were comparable to those from health controls. The proportion of Tγ cells, however, was significantly (P
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/61.5.1181