Proliferative function of cadaveric bone marrow cells

The proliferative function of human and murine cadaveric bone marrow was studied using methylcellulose clonal cell culture assays and the murine spleen colony technique. The study revealed persistence of hemopoietic functions for as long as 19 postmortem hours in cadaveric marrows of some patients....

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Veröffentlicht in:American journal of hematology 1978, Vol.5 (2), p.145-150
Hauptverfasser: Liu, Paul L., Ogawa, Makio, Crook, Lynn, Ochia, Roland, Upshur, Jane K.
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Sprache:eng
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Zusammenfassung:The proliferative function of human and murine cadaveric bone marrow was studied using methylcellulose clonal cell culture assays and the murine spleen colony technique. The study revealed persistence of hemopoietic functions for as long as 19 postmortem hours in cadaveric marrows of some patients. Studies of murine cadaveric marrows corresponded with those of human marrows. These results strongly suggest that human pluripotent hemopoietic stem cells survive in cadaveric marrows.
ISSN:0361-8609
1096-8652
DOI:10.1002/ajh.2830050210