Hormones, salt, hypertension and the interstitium. Is the interstitium the missing link?
The pathophysiology of most forms of hypertension is still poorly understood. A hypothesis is developed suggesting that the balance of hormones capable of influencing sodium metabolism play a significant role in the pathophysiology of hypertension, and that a significant component of the hormonal ef...
Gespeichert in:
Veröffentlicht in: | Medical hypotheses 1982-04, Vol.8 (4), p.413-422 |
---|---|
1. Verfasser: | |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The pathophysiology of most forms of hypertension is still poorly understood. A hypothesis is developed suggesting that the balance of hormones capable of influencing sodium metabolism play a significant role in the pathophysiology of hypertension, and that a significant component of the hormonal effect is mediated through changes in the interstitial matrix. It is suggested that the interstitial changes play a direct role in the increase in blood pressure and in bringing about many of the observed differences between hypertensive and normotensive states. |
---|---|
ISSN: | 0306-9877 1532-2777 |
DOI: | 10.1016/0306-9877(82)90035-4 |