Prolactin Binding Sites in the Rat Brain

Prolactin Binding Sites in the Rat Brain

The principles of the competitive-binding assay were used in conjunction with light microscopic radioautography to demonstrate specific prolactin binding sites localized on ependyma of the rat choroid plexus, a previously unknown prolactin target tissue.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1978-09, Vol.201 (4360), p.1041-1043
Hauptverfasser: Walsh, Raymond J., Posner, Barry I., Kopriwa, Beatrix M., Brawer, James R.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Arcuate nucleus
Autoradiography
Binding Sites
Binding, Competitive
Brain - cytology
Brain - metabolism
Choroid plexus
Ependyma
Female
Female animals
Hormones
Iodine Radioisotopes
Male
Median eminence
Porphyrias
Porphyrins
Prolactin - metabolism
Rats
Silver
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Beschreibung
Zusammenfassung:The principles of the competitive-binding assay were used in conjunction with light microscopic radioautography to demonstrate specific prolactin binding sites localized on ependyma of the rat choroid plexus, a previously unknown prolactin target tissue.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.684427