Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies

RUBACELL (Abbott Laboratories), a commercial test kit for the detection of rubella antibodies that utilizes the principle of passive hemagglutination (PHA), was compared with a standard hemagglutination-inhibition (HI) assay procedure. The PHA test gives a qualitative yes/no result suitable for preg...

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Veröffentlicht in:American journal of clinical pathology 1982-04, Vol.77 (4), p.462-464
Hauptverfasser: West, D J, Manty, A M, Siem, R A
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container_title American journal of clinical pathology
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creator West, D J
Manty, A M
Siem, R A
description RUBACELL (Abbott Laboratories), a commercial test kit for the detection of rubella antibodies that utilizes the principle of passive hemagglutination (PHA), was compared with a standard hemagglutination-inhibition (HI) assay procedure. The PHA test gives a qualitative yes/no result suitable for pregravidic determination of immune status. The procedure is technically simple and requires less than half the time needed for the HI assay. Four of 61 sera that were negative with HI assay tested as indeterminate or as falsely positive using the RUBACELL procedure.
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subjects Antibodies, Viral - analysis
Evaluation Studies as Topic
False Positive Reactions
Hemagglutination Inhibition Tests - methods
Hemagglutination Tests - instrumentation
Humans
Reagent Kits, Diagnostic
Rubella - immunology
rubella virus
title Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies
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