Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies
RUBACELL (Abbott Laboratories), a commercial test kit for the detection of rubella antibodies that utilizes the principle of passive hemagglutination (PHA), was compared with a standard hemagglutination-inhibition (HI) assay procedure. The PHA test gives a qualitative yes/no result suitable for preg...
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Veröffentlicht in: | American journal of clinical pathology 1982-04, Vol.77 (4), p.462-464 |
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container_title | American journal of clinical pathology |
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creator | West, D J Manty, A M Siem, R A |
description | RUBACELL (Abbott Laboratories), a commercial test kit for the detection of rubella antibodies that utilizes the principle of passive hemagglutination (PHA), was compared with a standard hemagglutination-inhibition (HI) assay procedure. The PHA test gives a qualitative yes/no result suitable for pregravidic determination of immune status. The procedure is technically simple and requires less than half the time needed for the HI assay. Four of 61 sera that were negative with HI assay tested as indeterminate or as falsely positive using the RUBACELL procedure. |
doi_str_mv | 10.1093/ajcp/77.4.462 |
format | Article |
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Four of 61 sera that were negative with HI assay tested as indeterminate or as falsely positive using the RUBACELL procedure.</description><subject>Antibodies, Viral - analysis</subject><subject>Evaluation Studies as Topic</subject><subject>False Positive Reactions</subject><subject>Hemagglutination Inhibition Tests - methods</subject><subject>Hemagglutination Tests - instrumentation</subject><subject>Humans</subject><subject>Reagent Kits, Diagnostic</subject><subject>Rubella - immunology</subject><subject>rubella virus</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEURoMotVaXLoWs3E1785jJZCmlPqDgRheuQjKTtKnzcpIp-O-d0upWuHAX99yPj4PQLYE5AckWeld0CyHmfM4zeoamRHKWCEHpOZoCAE0kEewSXYWwAyA0Bz5BEwGCZimfoo_VXleDjr5tcOuwxp0Owe8t3tpabzbVEH1zvEYbIv70Ebu2x3FrcWmjLX4f-8HYqtJYN9GbtvQ2XKMLp6tgb057ht4fV2_L52T9-vSyfFgnBSMyJg5S4cYBRmlOjRaEaGEKLUvHTQmZo85KyASQlBkrcjBSZym1LuPM5pKwGbo_5nZ9-zWMJVXtQ3Eo09h2CEpwSDmT6b8gGTGQlI9gcgSLvg2ht051va91_60IqINzdXCuhFBcjc5H_u4UPJjaln_0STL7AeWyfc4</recordid><startdate>198204</startdate><enddate>198204</enddate><creator>West, D J</creator><creator>Manty, A M</creator><creator>Siem, R A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7T7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>198204</creationdate><title>Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies</title><author>West, D J ; Manty, A M ; Siem, R A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-f057f57f032282ba711a7bca9df4bd06f2fe90670153be780b9a652ef643e8913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Antibodies, Viral - analysis</topic><topic>Evaluation Studies as Topic</topic><topic>False Positive Reactions</topic><topic>Hemagglutination Inhibition Tests - methods</topic><topic>Hemagglutination Tests - instrumentation</topic><topic>Humans</topic><topic>Reagent Kits, Diagnostic</topic><topic>Rubella - immunology</topic><topic>rubella virus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>West, D J</creatorcontrib><creatorcontrib>Manty, A M</creatorcontrib><creatorcontrib>Siem, R A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>West, D J</au><au>Manty, A M</au><au>Siem, R A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>1982-04</date><risdate>1982</risdate><volume>77</volume><issue>4</issue><spage>462</spage><epage>464</epage><pages>462-464</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><abstract>RUBACELL (Abbott Laboratories), a commercial test kit for the detection of rubella antibodies that utilizes the principle of passive hemagglutination (PHA), was compared with a standard hemagglutination-inhibition (HI) assay procedure. 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language | eng |
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source | MEDLINE; Oxford University Press Journals Digital Archive Legacy |
subjects | Antibodies, Viral - analysis Evaluation Studies as Topic False Positive Reactions Hemagglutination Inhibition Tests - methods Hemagglutination Tests - instrumentation Humans Reagent Kits, Diagnostic Rubella - immunology rubella virus |
title | Evaluation of a passive hemagglutination test kit for the detection of rubella antibodies |
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