Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome
Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lo...
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| Veröffentlicht in: | Chest 1982-06, Vol.81 (6), p.707-710 |
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| container_end_page | 710 |
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| container_issue | 6 |
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| container_title | Chest |
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| creator | Schiffman, Philip L. Remolina, Carlos Westlake, Robert E. Santiago, Teodoro V. Edelman, Norman H. |
| description | Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lower value of 64.4 ± 16.2 (P < 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims. |
| doi_str_mv | 10.1378/chest.81.6.707 |
| format | Article |
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Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lower value of 64.4 ± 16.2 (P < 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.81.6.707</identifier><identifier>PMID: 6804185</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Carbon Dioxide - physiology ; Humans ; Oxygen - physiology ; Parents ; Partial Pressure ; Respiration ; Respiratory Function Tests ; Sudden Infant Death - genetics</subject><ispartof>Chest, 1982-06, Vol.81 (6), p.707-710</ispartof><rights>1982 The American College of Chest Physicians</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-c858498395445813ed82c658f937c773ee5381417f272aacd4b310eb3bce0f663</citedby><cites>FETCH-LOGICAL-c378t-c858498395445813ed82c658f937c773ee5381417f272aacd4b310eb3bce0f663</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6804185$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schiffman, Philip L.</creatorcontrib><creatorcontrib>Remolina, Carlos</creatorcontrib><creatorcontrib>Westlake, Robert E.</creatorcontrib><creatorcontrib>Santiago, Teodoro V.</creatorcontrib><creatorcontrib>Edelman, Norman H.</creatorcontrib><title>Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome</title><title>Chest</title><addtitle>Chest</addtitle><description>Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lower value of 64.4 ± 16.2 (P < 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.</description><subject>Carbon Dioxide - physiology</subject><subject>Humans</subject><subject>Oxygen - physiology</subject><subject>Parents</subject><subject>Partial Pressure</subject><subject>Respiration</subject><subject>Respiratory Function Tests</subject><subject>Sudden Infant Death - genetics</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1P3DAURa2qiA602-4qedVdgh07sbNEQDsjIRXxtbU8zkvHKLGD7dDOv8cwo9INKz9L9x69dxD6SklJmZAnZgMxlZKWTSmI-IAWtGW0YDVnH9GCEFoVrGmrT-goxgeS_7RtDtFhIwmnsl4gdQ8u2UEnH7b4GuLkXQScPF5Fb_TkrMHL7eT_Wo2tw1c65HjEvsf31iQ7vo43c9eBwyvXa5fwOei0wTdb1wU_wmd00Oshwpf9e4zuflzcni2Ly18_V2enl4XJR6TCyFryVrK25ryWlEEnK9PUsm-ZMEIwgJpJyqnoK1FpbTq-ZpTAmq0NkL5p2DH6vuNOwT_OWYkabTQwDNqBn6MSnPCMrnKw3AVN8DEG6NUU7KjDVlGiXoyqV6NKUtWobDQXvu3J83qE7l98r_ANuLG_N39sABVHPQw5zXaoBz8Hp4f_gHJXgOzjyUJQ0VhwBrpcNkl13r63yzPpUJa8</recordid><startdate>198206</startdate><enddate>198206</enddate><creator>Schiffman, Philip L.</creator><creator>Remolina, Carlos</creator><creator>Westlake, Robert E.</creator><creator>Santiago, Teodoro V.</creator><creator>Edelman, Norman H.</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198206</creationdate><title>Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome</title><author>Schiffman, Philip L. ; Remolina, Carlos ; Westlake, Robert E. ; Santiago, Teodoro V. ; Edelman, Norman H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-c858498395445813ed82c658f937c773ee5381417f272aacd4b310eb3bce0f663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Carbon Dioxide - physiology</topic><topic>Humans</topic><topic>Oxygen - physiology</topic><topic>Parents</topic><topic>Partial Pressure</topic><topic>Respiration</topic><topic>Respiratory Function Tests</topic><topic>Sudden Infant Death - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schiffman, Philip L.</creatorcontrib><creatorcontrib>Remolina, Carlos</creatorcontrib><creatorcontrib>Westlake, Robert E.</creatorcontrib><creatorcontrib>Santiago, Teodoro V.</creatorcontrib><creatorcontrib>Edelman, Norman H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schiffman, Philip L.</au><au>Remolina, Carlos</au><au>Westlake, Robert E.</au><au>Santiago, Teodoro V.</au><au>Edelman, Norman H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>1982-06</date><risdate>1982</risdate><volume>81</volume><issue>6</issue><spage>707</spage><epage>710</epage><pages>707-710</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><abstract>Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lower value of 64.4 ± 16.2 (P < 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6804185</pmid><doi>10.1378/chest.81.6.707</doi><tpages>4</tpages></addata></record> |
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| ispartof | Chest, 1982-06, Vol.81 (6), p.707-710 |
| issn | 0012-3692 1931-3543 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Carbon Dioxide - physiology Humans Oxygen - physiology Parents Partial Pressure Respiration Respiratory Function Tests Sudden Infant Death - genetics |
| title | Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome |
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