Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome

Ventilatory Response to Isocapnic Hypoxia in Parents of Victims of Sudden Infant Death Syndrome

Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lo...

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Veröffentlicht in:Chest 1982-06, Vol.81 (6), p.707-710
Hauptverfasser: Schiffman, Philip L., Remolina, Carlos, Westlake, Robert E., Santiago, Teodoro V., Edelman, Norman H.
Format: Artikel
Sprache:eng
Schlagworte:
Carbon Dioxide - physiology
Humans
Oxygen - physiology
Parents
Partial Pressure
Respiration
Respiratory Function Tests
Sudden Infant Death - genetics
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Zusammenfassung:Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 ± 46.4, while SIDS parents had a significantly lower value of 64.4 ± 16.2 (P < 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.
ISSN:0012-3692
1931-3543
DOI:10.1378/chest.81.6.707