Maximum Tolerable Afterload and Afterload Reserve for the Evaluation of Ventricular Performance

The concept of a maximum tolerable afterload and an afterload reserve was proposed for evaluating ventricular function. A maximum tolerable afterload was defined as the systolic ventricular pressure during gradual proximal arterial obstruction, at the point where a distal arterial pressure or flow b...

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Veröffentlicht in:Japanese Heart Journal 1978, Vol.19(1), pp.84-93
Hauptverfasser: SUMA, Kozo, Tsuji, Takayuki
Format: Artikel
Sprache:eng
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Zusammenfassung:The concept of a maximum tolerable afterload and an afterload reserve was proposed for evaluating ventricular function. A maximum tolerable afterload was defined as the systolic ventricular pressure during gradual proximal arterial obstruction, at the point where a distal arterial pressure or flow began to fall. An afterload reserve was defined as the difference between a maximum tolerable afterload and a basal afterload. By using right heart bypass preparations in dogs, a maximum tolerable afterload and an afterload reserve were compared with the ventricular function curve. An improved ventricular function curve was always associated with a greater maximum tolerable afterload and a greater afterload reserve, whereas a depressed function curve with a smaller maximum tolerable afterload and a smaller afterload reserve.
ISSN:0021-4868
1348-673X
DOI:10.1536/ihj.19.84