Multiple Antibody Formation in a Primigravida: Anti-D, Anti-C, Anti-Kpb

A case of a primigravida in whom anti-C, anti-D, and anti- Kpb developed during the third trimester is described. Her first-born infant, delivered at 40 weeksʼ gestation, was mildly affected with hemolytic disease of the newborn and responded well to phototherapy. Her second-born infant, delivered at 36 weeksʼ gestation, had a positive direct antiglobulin test, but required no treatment. Clinical and laboratory aspects of both pregnancies are discussed. (Obstet Gynecol 59:10S, 1982)