An assessment of iopamidol, a non-ionic contrast medium, in aorto-femoral angiography

Iopamidol, a recently developed non-ionic contrast medium, was used for aorto-femoral angiography in a concentration of 370 mg of iodine/ml. The injection of 35–40 ml was painless in most cases and was never severe. A sensation of heat in the legs accompanied all injections. A fall in systolic and diastolic blood pressure and an increase in heart rate occurred, these effects being greater than with metrizamide. The image quality was satisfactory. Iopamidol is well tolerated and preferable to conventional hyperosmolar contrast media in aorto-femoral angiography.