Haemostatic effect of triglycylvasopressin on bleeding from gastric mucosal lesions in the rat

The haemostatic effect of triglycylvasopressin (TGLVP) on the gastric mucosa was evaluated in an experimental model in the rat. TGLVP was found to reduce the bleeding significantly compared with the untreated controls. The haemostatic effect was most prounounced and prolonged when 200 microgram/kg b...

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Veröffentlicht in:	Research in experimental medicine 1978-06, Vol.172 (2), p.131-135
Hauptverfasser:	Wetterlin, S, Ahlgren, I, Aronsen, K F, Mulder, J F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gastric Mucosa - injuries Gastrointestinal Hemorrhage - therapy Hemostasis - drug effects Injections, Intravenous Rats Vasopressins - administration & dosage Vasopressins - analogs & derivatives Vasopressins - therapeutic use
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Beschreibung
Zusammenfassung:	The haemostatic effect of triglycylvasopressin (TGLVP) on the gastric mucosa was evaluated in an experimental model in the rat. TGLVP was found to reduce the bleeding significantly compared with the untreated controls. The haemostatic effect was most prounounced and prolonged when 200 microgram/kg b.w. was given intravenously. The clinical application of this finding is discussed.
ISSN:	0300-9130 1433-8580
DOI:	10.1007/BF01851403