Effects of allogeneic peripheral stem cell transplantation in a patient with Job syndrome of hyperimmunoglobulinemia E and recurrent infections

Job syndrome of hyperimmunoglobulinemia E is defined by markedly elevated serum IgE levels and recurrent sinopulmonary and cutaneous infections. A patient with the syndrome developed lymphoma and underwent an allogeneic stem cell transplantation that restored several measures of his immune dysfuncti...

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Veröffentlicht in:	The American journal of medicine 1998-08, Vol.105 (2), p.162-164
Hauptverfasser:	Nester, Theresa A., Wagnon, Alton H., Reilly, William F., Spitzer, Gary, Kjeldsberg, Carl R., Hill, Harry R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cells Combined Modality Therapy Disease Fatal Outcome Hematologic and hematopoietic diseases Hematopoietic Stem Cell Transplantation Humans Infections Job Syndrome - complications Job Syndrome - immunology Job Syndrome - therapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - complications Lymphoma, B-Cell - therapy Lymphoma, Large B-Cell, Diffuse - complications Lymphoma, Large B-Cell, Diffuse - therapy Male Medical sciences Middle Aged Pulmonary Fibrosis - etiology Transplants & implants
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Beschreibung
Zusammenfassung:	Job syndrome of hyperimmunoglobulinemia E is defined by markedly elevated serum IgE levels and recurrent sinopulmonary and cutaneous infections. A patient with the syndrome developed lymphoma and underwent an allogeneic stem cell transplantation that restored several measures of his immune dysfunction, including the elevated IgE levels.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/S0002-9343(98)00200-9