Levamisole in the treatment of juvenile laryngeal papillomatosis

Three patients are described who were treated with levamisole for juvenile laryngeal papillomatosis. In two patients no effect of levamisole was noted during a treatment period of 8–9 months. In the third patient a remission of the disease was noted some months after starting levamisole treatment. In view of our experience with the other two patients the remission may be due to the capricious natural course of the disease rather than to the effect of levamisole. Levamisole does not seem to be an effective drug for the treatment of extensive juvenile papillomatosis and according to the literature not a harmless drug.