Antenatal screening for Down's syndrome: where are we and where next?

The use of screening procedures to identify Down's syndrome in babies of women over 35 has been around since the 1970s. In 1984, advances in the screening procedure allowed the test to be offered to younger women. Haddow discusses antenatal screening procedures and future expectations.

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Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 1998-08, Vol.352 (9125), p.336-337
1. Verfasser:	Haddow, James E
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Fetoproteins - analysis Amniocentesis Bioethics Biomarkers - blood Chorionic Gonadotropin - blood Chromosomes, Human, Pair 21 - genetics Down Syndrome - diagnosis Down Syndrome - diagnostic imaging Down Syndrome - genetics Down Syndrome - prevention & control Downs syndrome Estriol - blood Female Fetal Diseases - diagnosis Fetal Diseases - diagnostic imaging Fetal Diseases - genetics Fetal Diseases - prevention & control Genetic Markers - genetics Genetic Testing Humans Inhibins - blood Mass Screening Maternal Age Medical screening Polymerase Chain Reaction Pregnancy Pregnancy - blood Pregnancy, High-Risk Prenatal Diagnosis Ultrasonography, Prenatal Women
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Beschreibung
Zusammenfassung:	The use of screening procedures to identify Down's syndrome in babies of women over 35 has been around since the 1970s. In 1984, advances in the screening procedure allowed the test to be offered to younger women. Haddow discusses antenatal screening procedures and future expectations.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(98)22031-9