THE EFFECTS OF INDOMETHACIN IN TREATED HYPERTENSIVE PATIENTS

THE EFFECTS OF INDOMETHACIN IN TREATED HYPERTENSIVE PATIENTS

SUMMARY 1. Twelve treated hypertensive patients (ages 58–71 years) who had also been treated for joint disease participated in a randomized double‐blind crossover placebo‐controlled study to investigate the effects of indomethacin (25 mg three times daily) on blood pressure and biochemical parameter...

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Veröffentlicht in:Clinical and experimental pharmacology & physiology 1981-09, Vol.8 (5), p.537-541
Hauptverfasser: Wing, L. M. H., Bune, A. J. C., Chalmers, J. P., Graham, J. R., West, M. J.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
aldosterone
Aldosterone - blood
anti-inflammatory agents
antihypertensive agents
Antihypertensive Agents - therapeutic use
blood pressure
Blood Pressure - drug effects
Female
Humans
hypertension
Hypertension - drug therapy
indomethacin
Indomethacin - therapeutic use
Male
Middle Aged
prostaglandin synthase
prostaglandins
renin
Renin - blood
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Zusammenfassung:SUMMARY 1. Twelve treated hypertensive patients (ages 58–71 years) who had also been treated for joint disease participated in a randomized double‐blind crossover placebo‐controlled study to investigate the effects of indomethacin (25 mg three times daily) on blood pressure and biochemical parameters over a 6‐week period. 2. Blood pressure was increased in all patients throughout the indomethacin treatment period (P
ISSN:0305-1870
1440-1681
DOI:10.1111/j.1440-1681.1981.tb00763.x