Theophylline Analysis by Direct Application of Serum to Thin Layer Chromatograms

Theophylline Analysis by Direct Application of Serum to Thin Layer Chromatograms

The direct application of 20 μl of serum to thin layer chromatograms was a rapid and sensitive method for the determination of theophylline. Ten common drugs were shown not to interfere. A comparison with the enzyme immunoassay values obtained in an independent laboratory showed the utility of the m...

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Veröffentlicht in:Journal of chromatographic science 1981-11, Vol.19 (11), p.594-597
Hauptverfasser: Heilweil, Elaine, Touchstone, Joseph C.
Format: Artikel
Sprache:eng
Schlagworte:
Chromatography, Thin Layer - methods
Humans
Immunoenzyme Techniques
Infant, Newborn
Theophylline - blood
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Zusammenfassung:The direct application of 20 μl of serum to thin layer chromatograms was a rapid and sensitive method for the determination of theophylline. Ten common drugs were shown not to interfere. A comparison with the enzyme immunoassay values obtained in an independent laboratory showed the utility of the method.
ISSN:0021-9665
1945-239X
DOI:10.1093/chromsci/19.11.594