Postcoital antifertility effect of Mentha arvensis

A uterotonic fraction of Mentha arvensis (UM-fraction) was tested for antifertility effect in rats. Subcutaneous administration of the UM-fraction to rats pregnant from day 1 to day 10 caused a significant interruption in pregnancy. The effect was pronounced during the post-implantation period. At t...

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Veröffentlicht in:	Contraception (Stoneham) 1981-11, Vol.24 (5), p.559-567
Hauptverfasser:	Kanjanapothi, D, Smitasiri, Y, Panthong, A, Taesotikul, T, Rattanapanone, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Contraceptives, Postcoital Female Male Organ Size - drug effects Plant Extracts - pharmacology Plants, Medicinal Pregnancy Prostate - drug effects Rats Seminal Vesicles - drug effects Testis - drug effects Uterine Contraction - drug effects Uterus - drug effects Uterus - physiology
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Beschreibung
Zusammenfassung:	A uterotonic fraction of Mentha arvensis (UM-fraction) was tested for antifertility effect in rats. Subcutaneous administration of the UM-fraction to rats pregnant from day 1 to day 10 caused a significant interruption in pregnancy. The effect was pronounced during the post-implantation period. At the effective dose, the UM-fraction did not exhibit significant estrogenic or antigonadotropic activities. However, it enhanced the estrogenic effect of estradiol when administered concurrently.
ISSN:	0010-7824
DOI:	10.1016/0010-7824(81)90059-7