The lactate metabolism of the oral bacterium Veillonella from human saliva
Lactate is metabolized by Veillonella via the methylmalonyl-coenzyme A (CoA) pathway to propionate and, by further pathways, to acetate. Whereas pyruvate and oxaloacetate are metabolized via the pyruvate-formate lyase reaction, lactate acts as a donor of hydrogen allowing the reduction of oxaloaceta...
Gespeichert in:
| Veröffentlicht in: | Archives of oral biology 1981, Vol.26 (8), p.657-661 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 661 |
|---|---|
| container_issue | 8 |
| container_start_page | 657 |
| container_title | Archives of oral biology |
| container_volume | 26 |
| creator | Distler, W. Kröncke, A. |
| description | Lactate is metabolized by
Veillonella via the methylmalonyl-coenzyme A (CoA) pathway to propionate and, by further pathways, to acetate. Whereas pyruvate and oxaloacetate are metabolized via the pyruvate-formate lyase reaction, lactate acts as a donor of hydrogen allowing the reduction of oxaloacetate to malate in the methylmalonyl-CoA pathway. Succinate, believed to be an intermediate in lactate metabolism of
Veillonellae is readily decarboxylated to propionate by these organisms, but a severe, progressive substrate inhibition occurs at concentrations above 12–16 mmol/l. |
| doi_str_mv | 10.1016/0003-9969(81)90162-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73834918</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>000399698190162X</els_id><sourcerecordid>73834918</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-9722f4ec6ba8f9ccfb6c4e1fe7e0c88c8b4fffb5642fbab2997c7b559055e40b3</originalsourceid><addsrcrecordid>eNp9kMtKAzEUhoMotV7eQCEr0cVoMpdcNoKIVwpuqnQXkvSERjKNJjMF396pLV26Opzz_-f2IXRGyTUllN0QQqpCSiYvBb2SQ6UsZntoTAWXBW0I20fjneUQHeX8OaQNY3SERkzWnHM6Rq_TBeCgbac7wC102sTgc4ujw92gxKQDNoMMyfct_gAfQlxCCBq7FFu86Fu9xFkHv9In6MDpkOF0G4_R--PD9P65mLw9vdzfTQpbNbwrJC9LV4NlRgsnrXWG2RqoAw7ECmGFqZ1zpmF16Yw2pZTcctM0kjQN1MRUx-hiM_crxe8ecqdan-36piXEPiteiaqWVAzGemO0KeacwKmv5FudfhQlao1QrfmoNR8lqPpDqGZD2_l2fm9amO-atswG_Xajw_DkykNS2XpYWpj7BLZT8-j_X_ALCTGBmA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73834918</pqid></control><display><type>article</type><title>The lactate metabolism of the oral bacterium Veillonella from human saliva</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Distler, W. ; Kröncke, A.</creator><creatorcontrib>Distler, W. ; Kröncke, A.</creatorcontrib><description>Lactate is metabolized by
Veillonella via the methylmalonyl-coenzyme A (CoA) pathway to propionate and, by further pathways, to acetate. Whereas pyruvate and oxaloacetate are metabolized via the pyruvate-formate lyase reaction, lactate acts as a donor of hydrogen allowing the reduction of oxaloacetate to malate in the methylmalonyl-CoA pathway. Succinate, believed to be an intermediate in lactate metabolism of
Veillonellae is readily decarboxylated to propionate by these organisms, but a severe, progressive substrate inhibition occurs at concentrations above 12–16 mmol/l.</description><identifier>ISSN: 0003-9969</identifier><identifier>EISSN: 1879-1506</identifier><identifier>DOI: 10.1016/0003-9969(81)90162-X</identifier><identifier>PMID: 6947771</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Acetates - metabolism ; Dentistry ; Humans ; Lactates - metabolism ; Lactic Acid ; Oxaloacetates - metabolism ; Pyruvates - metabolism ; Pyruvic Acid ; Saliva - microbiology ; Succinates - metabolism ; Succinic Acid ; Veillonella - metabolism</subject><ispartof>Archives of oral biology, 1981, Vol.26 (8), p.657-661</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-9722f4ec6ba8f9ccfb6c4e1fe7e0c88c8b4fffb5642fbab2997c7b559055e40b3</citedby><cites>FETCH-LOGICAL-c357t-9722f4ec6ba8f9ccfb6c4e1fe7e0c88c8b4fffb5642fbab2997c7b559055e40b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/000399698190162X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6947771$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Distler, W.</creatorcontrib><creatorcontrib>Kröncke, A.</creatorcontrib><title>The lactate metabolism of the oral bacterium Veillonella from human saliva</title><title>Archives of oral biology</title><addtitle>Arch Oral Biol</addtitle><description>Lactate is metabolized by
Veillonella via the methylmalonyl-coenzyme A (CoA) pathway to propionate and, by further pathways, to acetate. Whereas pyruvate and oxaloacetate are metabolized via the pyruvate-formate lyase reaction, lactate acts as a donor of hydrogen allowing the reduction of oxaloacetate to malate in the methylmalonyl-CoA pathway. Succinate, believed to be an intermediate in lactate metabolism of
Veillonellae is readily decarboxylated to propionate by these organisms, but a severe, progressive substrate inhibition occurs at concentrations above 12–16 mmol/l.</description><subject>Acetates - metabolism</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Lactates - metabolism</subject><subject>Lactic Acid</subject><subject>Oxaloacetates - metabolism</subject><subject>Pyruvates - metabolism</subject><subject>Pyruvic Acid</subject><subject>Saliva - microbiology</subject><subject>Succinates - metabolism</subject><subject>Succinic Acid</subject><subject>Veillonella - metabolism</subject><issn>0003-9969</issn><issn>1879-1506</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKAzEUhoMotV7eQCEr0cVoMpdcNoKIVwpuqnQXkvSERjKNJjMF396pLV26Opzz_-f2IXRGyTUllN0QQqpCSiYvBb2SQ6UsZntoTAWXBW0I20fjneUQHeX8OaQNY3SERkzWnHM6Rq_TBeCgbac7wC102sTgc4ujw92gxKQDNoMMyfct_gAfQlxCCBq7FFu86Fu9xFkHv9In6MDpkOF0G4_R--PD9P65mLw9vdzfTQpbNbwrJC9LV4NlRgsnrXWG2RqoAw7ECmGFqZ1zpmF16Yw2pZTcctM0kjQN1MRUx-hiM_crxe8ecqdan-36piXEPiteiaqWVAzGemO0KeacwKmv5FudfhQlao1QrfmoNR8lqPpDqGZD2_l2fm9amO-atswG_Xajw_DkykNS2XpYWpj7BLZT8-j_X_ALCTGBmA</recordid><startdate>1981</startdate><enddate>1981</enddate><creator>Distler, W.</creator><creator>Kröncke, A.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1981</creationdate><title>The lactate metabolism of the oral bacterium Veillonella from human saliva</title><author>Distler, W. ; Kröncke, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-9722f4ec6ba8f9ccfb6c4e1fe7e0c88c8b4fffb5642fbab2997c7b559055e40b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Acetates - metabolism</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Lactates - metabolism</topic><topic>Lactic Acid</topic><topic>Oxaloacetates - metabolism</topic><topic>Pyruvates - metabolism</topic><topic>Pyruvic Acid</topic><topic>Saliva - microbiology</topic><topic>Succinates - metabolism</topic><topic>Succinic Acid</topic><topic>Veillonella - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Distler, W.</creatorcontrib><creatorcontrib>Kröncke, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of oral biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Distler, W.</au><au>Kröncke, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The lactate metabolism of the oral bacterium Veillonella from human saliva</atitle><jtitle>Archives of oral biology</jtitle><addtitle>Arch Oral Biol</addtitle><date>1981</date><risdate>1981</risdate><volume>26</volume><issue>8</issue><spage>657</spage><epage>661</epage><pages>657-661</pages><issn>0003-9969</issn><eissn>1879-1506</eissn><abstract>Lactate is metabolized by
Veillonella via the methylmalonyl-coenzyme A (CoA) pathway to propionate and, by further pathways, to acetate. Whereas pyruvate and oxaloacetate are metabolized via the pyruvate-formate lyase reaction, lactate acts as a donor of hydrogen allowing the reduction of oxaloacetate to malate in the methylmalonyl-CoA pathway. Succinate, believed to be an intermediate in lactate metabolism of
Veillonellae is readily decarboxylated to propionate by these organisms, but a severe, progressive substrate inhibition occurs at concentrations above 12–16 mmol/l.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>6947771</pmid><doi>10.1016/0003-9969(81)90162-X</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-9969 |
| ispartof | Archives of oral biology, 1981, Vol.26 (8), p.657-661 |
| issn | 0003-9969 1879-1506 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73834918 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acetates - metabolism Dentistry Humans Lactates - metabolism Lactic Acid Oxaloacetates - metabolism Pyruvates - metabolism Pyruvic Acid Saliva - microbiology Succinates - metabolism Succinic Acid Veillonella - metabolism |
| title | The lactate metabolism of the oral bacterium Veillonella from human saliva |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T14%3A05%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20lactate%20metabolism%20of%20the%20oral%20bacterium%20Veillonella%20from%20human%20saliva&rft.jtitle=Archives%20of%20oral%20biology&rft.au=Distler,%20W.&rft.date=1981&rft.volume=26&rft.issue=8&rft.spage=657&rft.epage=661&rft.pages=657-661&rft.issn=0003-9969&rft.eissn=1879-1506&rft_id=info:doi/10.1016/0003-9969(81)90162-X&rft_dat=%3Cproquest_cross%3E73834918%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73834918&rft_id=info:pmid/6947771&rft_els_id=000399698190162X&rfr_iscdi=true |