NEW RIFAMYCINS PRODUCED BY A RECOMBINANT STRAIN OF NOCARDIA MEDITERRANEI

NEW RIFAMYCINS PRODUCED BY A RECOMBINANT STRAIN OF NOCARDIA MEDITERRANEI

A recombinant strain of Nocardia mediterranei was found to produce a number of new rifamycins which are structurally related to rifamycin S, rifamycin W and rifamycin G. This strain was derived from two Nocardia mediterranei mutants by intraspecific recombination.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of antibiotics 1981, Vol.34(8), pp.965-970
Hauptverfasser: SCHUPP, T., TRAXLER, P., AUDEN, J. A. L.
Format: Artikel
Sprache:eng
Schlagworte:
Biotransformation
Fermentation
Nocardia - genetics
Nocardia - metabolism
Recombination, Genetic
Rifamycins - biosynthesis
Rifamycins - isolation & purification
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Beschreibung
Zusammenfassung:A recombinant strain of Nocardia mediterranei was found to produce a number of new rifamycins which are structurally related to rifamycin S, rifamycin W and rifamycin G. This strain was derived from two Nocardia mediterranei mutants by intraspecific recombination.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.34.965