Urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in the rat after immobilization stress

Urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA) in the rat after immobilization stress

An increase of 100% in urinary 5-hydroxyindoleacetic acid, as a measure of release and catabolism of serotonin, is associated with the stress of 18 hr of restraint. Seventy percent of the rats developed gastric ulcers. Increased urinary 5-hydroxyindoleacetic acid levels were not observed in rats dep...

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Veröffentlicht in:Physiology & behavior 1977-12, Vol.19 (6), p.739-741
Hauptverfasser: Kundrotas, Leon W., Gregg, Robert V.
Format: Artikel
Sprache:eng
Schlagworte:
5-Hydroxyindoleacetic acid (5-HIAA)
Animals
Female
Hydroxyindoleacetic Acid - urine
Immobilization stress
Male
Rats
Restraint ulcer
Restraint, Physical
Serotonin (5-HT)
Serotonin - metabolism
Stomach Ulcer - etiology
Stomach Ulcer - metabolism
Stomach Ulcer - urine
Stress, Physiological - complications
Stress, Physiological - metabolism
Stress, Physiological - urine
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Zusammenfassung:An increase of 100% in urinary 5-hydroxyindoleacetic acid, as a measure of release and catabolism of serotonin, is associated with the stress of 18 hr of restraint. Seventy percent of the rats developed gastric ulcers. Increased urinary 5-hydroxyindoleacetic acid levels were not observed in rats deprived of food for 42 hr.
ISSN:0031-9384
1873-507X
DOI:10.1016/0031-9384(77)90308-0