Succinimides With Oxyacetate Side Chain as Potential Anticonvulsant Agents

Two new compounds, ethyl N-succinimidoxyacetate and methyl N-succinimidoxyacetate, were prepared by reacting a solution of freshly recrystallized N-hydroxysuccinimide in tetrahydrofuran with a mixture of the corresponding halogenated ester and triethylamine. The compounds possessed some anticonvulsa...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1981-08, Vol.70 (8), p.963-963
Hauptverfasser:	Owoyale, J.A., Lahan, G.D., Osuide, G., Edafiogho, I.O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anticonvulsant effects Anticonvulsants - chemical synthesis Anticonvulsants-succinimide derivatives Anticonvulsants—succinimide derivatives, synthesis and analysis Chickens Derivatives-of succinimides Derivatives—of succinimides, synthesis and analysis Succinimides - chemical synthesis Succinimides - pharmacology Succinimides-derivatives Succinimides—derivatives, anticonvulsant effects, synthesis and analysis synthesis and analysis
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Beschreibung
Zusammenfassung:	Two new compounds, ethyl N-succinimidoxyacetate and methyl N-succinimidoxyacetate, were prepared by reacting a solution of freshly recrystallized N-hydroxysuccinimide in tetrahydrofuran with a mixture of the corresponding halogenated ester and triethylamine. The compounds possessed some anticonvulsant properties.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600700838