The regulation of the T-lymphocytes precursor pool by a humoral factor released by the thymus

The regulation of the T-lymphocytes precursor pool by a humoral factor released by the thymus

Studies in congenitally athymic nude mice grafted with syngeneic thymus enclosed or not in a cell-impermeable Millipore chamber show that the thymus secretes one or several humoral factors controlling the size of the pool of early T-lineage cells produced by the bone marrow.

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Veröffentlicht in:Cellular immunology 1977-12, Vol.34 (2), p.420-423
Hauptverfasser: Roelants, Georges E., Mayor-Withey, Kathleen S.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies - pharmacology
Antibody Formation
Cell Differentiation
Mice
Mice, Nude
T-Lymphocytes - cytology
T-Lymphocytes - physiology
Thymus Gland - immunology
Thymus Gland - physiology
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Zusammenfassung:Studies in congenitally athymic nude mice grafted with syngeneic thymus enclosed or not in a cell-impermeable Millipore chamber show that the thymus secretes one or several humoral factors controlling the size of the pool of early T-lineage cells produced by the bone marrow.
ISSN:0008-8749
1090-2163
DOI:10.1016/0008-8749(77)90264-7