The effects of gamma-irradiation on the hydration characteristics of DNA and polynucleotides. III. A comparative NMR study of frozen and liquid solutions

The effects of gamma-irradiation and changes in the macromolecular structure on the water proton resonance spectra observed in frozen and liwuid solutions have been compared for the DNA and polynucleotide solutions, using H2O or mixed H2O/D2O solvents. The results indicate that in order to obtain in...

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Veröffentlicht in:	Radiation and environmental biophysics 1977-12, Vol.14 (4), p.311-315
Hauptverfasser:	Mathur-De Vré, R, Bertinchamps, A J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cold Temperature DNA - radiation effects Gamma Rays Magnetic Resonance Spectroscopy Polyribonucleotides - radiation effects
Online-Zugang:	Volltext
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Zusammenfassung:	The effects of gamma-irradiation and changes in the macromolecular structure on the water proton resonance spectra observed in frozen and liwuid solutions have been compared for the DNA and polynucleotide solutions, using H2O or mixed H2O/D2O solvents. The results indicate that in order to obtain information concerning the role of hydration water in mediating the overall radiation damage, the NMR studies must be performed in the frozen state.
ISSN:	0301-634X
DOI:	10.1007/BF01325246