A new test of exocrine pancreatic function using N-benzoyl-L-tyrosyl-p-aminobenzoic acid: Part II. The correlation of PFD and chymotrypsin output during PS-test

N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BTPABA), a new synthetic peptide is specifically hydrolyzed by chymotrypsin to yield p-aminobenzoic acid (PABA), which is estimated colorimetrically by diazotizing. The method suitable for assay of chymotrypsin in duodenal aspirates was investigated using BTP...

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Veröffentlicht in:Nippon Shokakibyo Gakkai Zasshi 1977/10/05, Vol.74(10), pp.1337-1346
1. Verfasser: KINUGASA, Katsuhiko
Format: Artikel
Sprache:jpn
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Zusammenfassung:N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BTPABA), a new synthetic peptide is specifically hydrolyzed by chymotrypsin to yield p-aminobenzoic acid (PABA), which is estimated colorimetrically by diazotizing. The method suitable for assay of chymotrypsin in duodenal aspirates was investigated using BTPABA as a substrate. Then the chymotrypsin output during PS-test was estimated in the patients with pancreatic disorder. The chymotrypsin output significantly correlated to the trypsin output (P
ISSN:0446-6586
1349-7693
DOI:10.11405/nisshoshi1964.74.1337