STUDIES ON THE IONOPHOROUS ANTIBIOTICS. XXVII: THE STRUCTURES OF TM-531B (4'-O-DEM ETHYLDIANEM YCIN) AND TM-531C(3'-HYDROXYDIANEMYCIN), NEW POLYETHER ANTIBIOTICS CONTAINING SUGARS OTHER THAN 4-O-METHYL AMICETOSE

In course of a screening program for these new substances, two polyether antibiotics TM-531B and TM-531C have been isolated as their sodium salts from the fermentation broth of Streptomyces hygroscopicus TM-531, a producing organism of leuseramycin and dianemycin. Their physicochemical properties re...

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Veröffentlicht in:	Journal of antibiotics 1981, Vol.34(10), pp.1369-1373
Hauptverfasser:	MIZUTANI, TAKU, YAMAGISHI, MICHIO, MIZOUE, KAZUTOSHI, KAWASHIMA, AKIRA, OMURA, SADAFUMI, OZEKI, MASAHIRO, SETO, HARUO, OTAKE, NOBORU
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides Anti-Bacterial Agents Chemical Phenomena Chemistry Glycosides Ionophores Magnetic Resonance Spectroscopy Streptomyces hygroscopicus
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container_title	Journal of antibiotics
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creator	MIZUTANI, TAKU YAMAGISHI, MICHIO MIZOUE, KAZUTOSHI KAWASHIMA, AKIRA OMURA, SADAFUMI OZEKI, MASAHIRO SETO, HARUO OTAKE, NOBORU
description	In course of a screening program for these new substances, two polyether antibiotics TM-531B and TM-531C have been isolated as their sodium salts from the fermentation broth of Streptomyces hygroscopicus TM-531, a producing organism of leuseramycin and dianemycin. Their physicochemical properties revealed that both are closely related congeners of dianemycin. This communication deals with their structural elucidation mainly based on the use of super(13)C NMR spectroscopy.
doi_str_mv	10.7164/antibiotics.34.1369
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subjects	Aminoglycosides Anti-Bacterial Agents Chemical Phenomena Chemistry Glycosides Ionophores Magnetic Resonance Spectroscopy Streptomyces hygroscopicus
title	STUDIES ON THE IONOPHOROUS ANTIBIOTICS. XXVII: THE STRUCTURES OF TM-531B (4'-O-DEM ETHYLDIANEM YCIN) AND TM-531C(3'-HYDROXYDIANEMYCIN), NEW POLYETHER ANTIBIOTICS CONTAINING SUGARS OTHER THAN 4-O-METHYL AMICETOSE
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